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SpaceX
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NASA
СпутникиРНSpaceXРоскосмосNASABackground In India, nearly one-fourth of the population has hypertension, and only 17.5% of them have their blood pressure under control. Utilizing a smartphone application for hypertension care could potentially address the unmet needs within the existing healthcare delivery system. However, individuals with hypertension are the primary stakeholders for the implementation of such smartphone application-based care. Therefore, identifying the factors that influence the acceptance of a smartphone application-based care among individuals with hypertension is a prerequisite. Aim This study aimed to identify factors influencing acceptance of smartphone application among people with hypertension using the extended Unified Theory of Acceptance and Use of Technology (UTAUT) model with age, gender, education, digital health literacy, m-health experience, status of blood pressure and its risk factors. Method In this cross-sectional survey, 134 individuals with hypertension, aged 30–79 years, were recruited from public and private healthcare facilities located in both urban and rural areas. All participants completed the self-administered questionnaire. Results Individuals who perceived the application to be easy to use were 9.79 (95% CI: 2.45–39.16, p - 0.001) times, and those who had the necessary technical resources and knowledge were 5.6 (95% CI: 1.86–16.80, p - 0.002) times more likely to accept smartphone application-based care. Other variables were either insignificant or had negligible influence on smartphone application-based care. Conclusion The availability of technical resources and knowledge, as well as ease of use, are significant predictors of smartphone application acceptance among individuals with hypertension. Implications Developers and policy-makers should consider incorporating these factors in developing and disseminating smartphone application-based care among individuals with hypertension.