A young girl from Louisiana has died after being infected with a brain-eating amoeba she likely contracted while swimming in a local lake.

Lillian Smart succumbed to primary amebic meningoencephalitis on Saturday – just one day after her eighth birthday, her parents said in a heartbreaking post on the Love for Lillian Facebook page.

She likely became infected after she went swimming at Lake Claiborne and came in contact with the amoeba Naegleria fowleri, which traveled up her nose and into the brain, the Louisiana Department of Health has said.

'Last night, Lillian ran from our arms to the arms of Jesus,' the girl's parents wrote. 'The injuries to her brain were too severe for her little body to recover from.' 

'Everyone did everything they could to keep her here,' the parents continued, noting they are 'heartbroken and honestly do not know what to do next.

'How do we put one foot in front of the other without our girl?'

After hearing the news, Louisiana Governor Jeff Landry shared his condolences on social media.

'Heartbroken over the news of Lillian's passing,' he posted on X. 'Please join Sharon and me in prayer for the Smart family and the entire Ruston community during this time.'

Senator John Kennedy also said he and his wife were 'heartbroken' by the news.

'Our hearts and prayers are with Lillian’s family, Ruston and all of Louisiana as we mourn this sweet little girl,' he posted on Facebook

'May God comfort her family and give them strength in the days ahead.'

Smart was first hospitalized on April 15, days after her trip to the lake, KNOE reports.

An online fundraiser that had been set up to help the family with her hospital bills said she started off having a fever on August 13, but she quickly developed double vision 'and other concerning symptoms.'

Her parents then rushed her to Willis-Knighton South, where doctors originally diagnosed her with bacterial meningitis before realizing they were dealing with a Naegleria fowleri infection. 

Smart is now remembered around the community for her joy.

'She's just always a happy child,' Patricia Willis, owner of The Children's Shoppe and Peach Lemonade in Ruston, told KNOE.

'Every time you see her, she has a smile on her face.' 

As Smart's parents now grapple with the loss of their beloved daughter, they said they will lean on their Christian faith and community.

'Our foundation is still in Jesus,' they noted.

'We didn't get to keep our girl, but we watched miracles happen on her behalf.'

They then went on to share their belief in God, saying: 'He will give us strength when we have none left. He's given us a community of support that I don't think can be found anywhere else in the world.

'Lil would have loved seeing everyone come together and she would have been right in the middle of it trying to help where she could,' the heartbroken parents said. 

They then asked for prayers.

'We are devastated. We know you are too,' they wrote. 'Pray for our boys. They are going to need it so much. Pray for our friends and family; they are so sad and somehow still showing up for us. Pray for us, we won't be able to do this without it.'

The couple concluded the post by saying they 'are so grateful to you for loving our girl.' 

Naegleria fowleri is commonly found in warm freshwater lakes, rivers, canals and ponds across the United States. It can cause primary amebic meningoencephalitis, a brain infection that is nearly always fatal.

There have been only 180 known cases of primary amebic meningoencephalitis in the US from 1937 through 2025. 

The most recent fatality from the infection in Louisiana occurred in St Bernard Parish in 2013 when four-year-old Drake Smith Jr contracted the amoeba while playing on a slip-and-slide, the Louisiana Illuminator reports.

Officials confirmed the presence of the amoeba in the household's water, but tests for the pathogen in the water system were negative. Still, parish officials detected low levels of chlorine and immediately treated the water system. 

Two years prior, a St Bernard Parish man died from an infection after using tap water for a sinus rinse and a DeSoto Parish woman died after using tap water there for a similar treatment.

Symptoms typically begin with a headache, fever, nausea and vomiting, before progressing to a stiff neck, seizure and a coma before death within about a week or two, according to the Centers for Disease Control and Prevention.

Symptoms typically appear within about five days after an infection and are fatal in 97 percent of cases. 

To reduce one's risk, experts advise holding your nose or wearing a nose clip if you are jumping or diving into fresh water, keeping your head above the water in hot springs and using distilled or boiled tap water when rinsing your sinuses or cleansing your nasal passages.