Patient preference and adherence research highlight potential of long-acting dosing regimens to improve clinical outcomes in severe asthma
Respiratory Biologics
Depemokimab
Depemokimab Demonstrates Sustained Long-Term Efficacy and Consistent Patient-Reported Outcomes Over 2 Years in Patients with Type 2 Asthma Irrespective of Baseline Inhaled Corticosteroid Dose: An Integrated Analysis of the Phase III SWIFT-1/-2 and the Open-Label Extension AGILE Studies
Reynold A. Panettieri
Poster Discussion — Presentation #519 — Session B22
Depemokimab Demonstrates Sustained Long-Term Efficacy and Consistent Patient-Reported Outcomes Over 2 Years in Patients with Type 2 Asthma and Chronic Rhinosinusitis with Nasal Polyps: An Integrated Analysis of the Phase III SWIFT-1/-2 and the Open Label Extension AGILE Studies
Ian D. Pavord
Poster Discussion — Presentation #520 — Session B22
Twice-Yearly Depemokimab Is Well Tolerated Over 2 Years in Patients with Type 2 Asthma: An Integrated Safety Analysis of the Phase III SWIFT-1/-2 and the Open-Label Extension AGILE Studies
Arnaud Bourdin
Thematic Poster — Presentation #P1391 — Session B32
Depemokimab Demonstrates Sustained Long-Term Efficacy and Consistent Patient-Reported Outcomes Over 2 Years in Patients with Type 2 Asthma: An Integrated Analysis of the SWIFT-1/-2 and AGILE Studies
Ian D. Pavord
Thematic Poster — Presentation #P1396 — Session B32
Blood Eosinophil Counts Are Positively Correlated with Type 2 Cytokine (IL-4, IL-5, and IL-13) Levels in Patients with Severe Asthma: Pooled Post Hoc Analysis of Data from SWIFT-1/-2 Studies
Geoffrey Chupp
Thematic Poster — Presentation #P1404 — Session A32
Patients in the US with Moderate to Severe Asthma and/or CRSwNP Prefer 6-Monthly Biologic Dosing Compared to More Frequent Biologic Dosing Schemes
Arijita Deb
Thematic Poster — Presentation #P1424 — Session B32
Efficacy and Safety of Twice-Yearly Depemokimab in Adolescent Patients with Asthma: Subgroup Analysis of the SWIFT-1/-2 Studies
Daniel J. Jackson
Thematic Poster — Presentation #P1388 — Session B32
When Patients Stay, Outcomes Improve: Real-World Evidence from Multiple Asthma Biologic Studies
Justin Kwiatek
Thematic Poster — Presentation #P1411 — Session B32
Who Receives Biologics? Comparative Real-World Insights into Biologic Access and Adherence in Severe Asthma in the USA
Justin Kwiatek
Oral Presentation — Session C14
Depemokimab vs Mepolizumab: Immuno-PET Imaging to Evaluate the Impact of YTE Modification on Tissue Distribution in Cynomolgus Monkeys
Hasan Alsaid
Thematic Poster — Presentation #P386 — Session C70
Variation of Clinical Characteristics and Disease Burden in Subgroups of Patients with Eosinophilic Granulomatosis With Polyangiitis (EGPA)
Tham T. Le
Poster Discussion — Presentation #411 — Session D23
Mepolizumab
Disease Stability Is Achievable in a Wide Spectrum of Patients with Chronic Obstructive Pulmonary Disease Receiving Mepolizumab: Pooled Results from Phase III Randomized Controlled Trials
Dave Singh
Thematic Poster — Presentation #P1506 — Session A34
Mepolizumab Reduces the Burden of Chronic Obstructive Pulmonary Disease Exacerbations in a Wide Spectrum of Patients: Pooled Results from Phase III Randomized Controlled Trials
Gerard J. Criner
Thematic Poster — Presentation #P1496 — Session A34
Mepolizumab Is Associated with Reductions in Exacerbations and Oral Corticosteroid Use in a Real-World Setting Among US Patients with Chronic Obstructive Pulmonary Disease
Sunay Shah
Thematic Poster — Presentation #P1504 — Session A34
Mepolizumab Is Associated with Reductions in Healthcare Resource Utilization in a Real-World Setting Among US Patients with Chronic Obstructive Pulmonary Disease
Rosirene Paczkowski
Thematic Poster — Presentation #P1505 — Session A34
Mepolizumab Reduces Type-2 COPD Exacerbations Requiring Systemic Corticosteroids in a Wide Spectrum of Patients: Pooled Results from Phase III Randomized Controlled Trials
Nicola Hanania
Thematic Poster — Presentation #P1430 — Session B32
Patients with Chronic Obstructive Pulmonary Disease with Exacerbations and Triple Therapy Linked to Increased Clinical and Economic Burden: US Database Claims Analysis
David Mannino
Thematic Poster — Presentation #P1515 — Session A34
Mepolizumab in Severe Asthma With and Without Comorbid Chronic Rhinosinusitis with Nasal Polyps: Long‑Term Real‑World Evidence from the TYREX Study
Luis Alejandro Pérez de Llano
Thematic Poster — Presentation #P47 — Session C33
Impact of Baseline Eosinophil Thresholds on Long-Term Outcomes in Severe Asthma Patients Receiving Mepolizumab: A Retrospective Multicenter Analysis
Luis Alejandro Pérez de Llano
Thematic Poster — Presentation #P48 — Session C33
Inhaled Therapeutics
Salbutamol MDI
Developing Low-Carbon Salbutamol MDI: Assessment of Safety and Tolerability of Salbutamol with Propellant HFA-152a
Maximilian Plank
Thematic Poster — Presentation #P1394 — Session A32
Patient Insights on Experience With Metered-Dose Inhalers Using Novel Low-Carbon Propellant HFA-152a Compared With the Current Propellant HFA-134a
Ruth Tal-Singer
Thematic Poster — Presentation #P1424 — Session A32
Fluticasone Furoate, Umeclidinium & Vilanterol
Effectiveness of Once‑Daily Single-Inhaler Triple Therapy Versus Dual Bronchodilator Therapy in Patients with Mild‑to‑Moderate COPD in Japan (TRACK Study)*
Koichiro Takahashi
Thematic Poster — Presentation #P1488 — Session A34
Impact of Immediate Diagnosis and Treatment on Recovery from COPD Exacerbations During Pulmonary Rehabilitation*
Rainer Gloeckl
Oral Presentation — Session C97
Improved Clinical Outcomes and Achievability of Clinical Remission After Initiation of Fluticasone Furoate/Umeclidinium/Vilanterol in Patients with Asthma in the United States
Rosirene Paczkowski
Thematic Poster — Presentation #P988 — Session B40
Defining Disease Stability in COPD: A Post Hoc Analysis of the Phase III IMPACT Trial
MeiLan K. Han
Oral Presentation — Session A16
Refractory Chronic Cough
Camlipixant
Prevalence of Refractory Chronic Cough and Unexplained Chronic Cough in Older Adults (≥65 Years) Based on a Claims Algorithm Using Medicare Fee-for-Service Administrative Claims Data
Krishna Sundar
Thematic Poster — Presentation #P71 — Session B39
Chart Review of Real-World Characteristics and Treatment Patterns of Patients with Refractory or Unexplained Chronic Cough in the United States
Michael Ghobrial
Thematic Poster — Presentation #P72 — Session B39
Clinical Characteristics, Disease Burden, and Treatments in Adult Patients with Refractory Chronic Cough/Unexplained Chronic Cough: A Systematic Literature Review
Julie Rouette
Thematic Poster — Presentation #P1043 — Session B58
Respiratory Portfolio
Predictive Validity of Three Definitions of Chronic Bronchitis (MRC, SGRQ, and CAT) in COPD
Fengyan Wang
Poster Discussion — Presentation #507 — Session B102
Mucus Plugging, Air Trapping and Emphysema in Healthy Young Adult Never-Smokers, Young Adult Smokers with Preserved Lung Function, and COPD Patients*
Aaron Braddy-Green
Poster Discussion — Presentation #818 — Session D30
Acute Respiratory Events in Symptomatic Smokers Are Associated with Accelerated Lung Function Decline in the British Early COPD Network (BEACON) Cohort*
Andrew I. Ritchie
Poster Discussion — Presentation #801 — Session D30
Lobar Mucus Plugging Identifies Regions of Air Trapping in Smokers with Preserved Lung Function (BEACON) and COPD*
Aaron Braddy-Green
Oral Presentation — Session D96
Pipeline
Targeted Literature Review of Idiopathic Pulmonary Fibrosis (IPF) Epidemiology and Antifibrotic Treatment Discontinuation
Philip L. Molyneaux
Poster Discussion — Presentation #512 — Session C103