In a new analysis of the SELECT trial published in JAMA Cardiology, semaglutide 2.4 mg improved clinical outcomes compared with placebo regardless of frailty level.For the analysis, the 17,604 patients (mean age, 61.6 years; 72.3% men) from SELECT, a trial that demonstrated semaglutide 2.4 mg (Wegovy, Novo Nordisk) reduced risk for major cardiovascular outcomes by 20% compared with placebo, were stratified into three categories according to a 31-item frailty index: not frail (31%), more frail (47%) and most frail (22%).“Practice is currently highly variable, which is due, in part, to
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|---|---|---|---|---|
| 1 | Scientists discover why Ozempic and Wegovy weight loss eventually plateaus | 0 | 12.8 | 25-05-2026 |
| 2 | Eli Lilly's Mounjaro shows heart health benefits in head-to-head trial with older diabetes drug Trulicity | 2 | 7 | 31-07-2025 |
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| 4 | Замедляет ли "Оземпик" процесс старения, рассказал ученый из МФТИ | 0 | 7.6 | 22-09-2026 |
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| 6 | Dr. Reddy’s to delay semaglutide supplies due to quality issue, shares hit | -2 | 6 | 09-07-2026 |
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| 8 | A New Understanding of HFpEF in Severe Obesity | 0 | 7.54 | 23-06-2026 |
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