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Спутники
РН
SpaceX
Роскосмос
NASA
СпутникиРНSpaceXРоскосмосNASAMosaic loss of Y chromosome is a common genetic phenomenon in elderly men. It predisposes affected individuals to cancers, suggesting that genes on this male-specific chromosome contribute to the well-being of men. Currently, the putative gene(s) responsible for such cancer predisposition when lost is/are currently unknown. A recent study identified the testis-specific protein Y-encoded (TSPY) gene possesses significant immunogenicity, capable of eliciting significant immune responses against and eliminating positive tumor cells in a mouse model of liver cancer. TSPY is a male-specific cancer-testis antigen expressed in a wide variety of cancers but not normal somatic cells. It is an ampliconic gene constituting a majority (~ 42%) of all protein-coding genes on the human Y chromosome. TSPY is hypothesized to be a guardian gene for man, protecting man from cancer development. Its high copy-number of conserved functional units ensures that it is intrinsically activated in early/progenitor...
| # | Наименование новости | Тональность | Информативность | Дата публикации |
|---|---|---|---|---|
| 1 | The human testis-specific protein Y-linked (TSPY) is a male-specific cancer-testis antigen capable of eliciting significant immune responses and elimination of positive tumor cells in hepatocellular carcinoma | 0 | 11.86 | 27-08-2026 |
| 2 | Das Krebswachstum bekämpfen | 0 | 16.39 | 21-07-2026 |
| 3 | SRY interference of normal regulation of the RET gene suggests a potential role of the Y-chromosome gene in sexual dimorphism in Hirschsprung disease | 0 | 8.19 | 27-08-2026 |
| 4 | Очень низкий уровень тестостерона связали с повышенным риском рака | 0 | 7 | 30-06-2026 |
| 5 | This yeast supplement may boost cancer-fighting immunity | 0 | 13.71 | 22-08-2026 |
| 6 | Study solves testosterone's paradoxical effects in prostate cancer | 0 | 8 | 04-09-2024 |
| 7 | Un tejido testicular congelado durante 16 años vuelve a producir espermatozoides | 0 | 10.13 | 21-07-2026 |
| 8 | Why the same DNA damage causes cancer in some people but not others | 0 | 7.49 | 27-07-2026 |
| 9 | Autoantibodies could shape cancer risk, growth and response to immunotherapy | 0 | 9.66 | 25-07-2026 |