Considerations Regarding Valved Holding Chamber Efficiency

Дата публикации: 01-08-2026 00:00:00

To the Editor The randomized clinical trial by Csonka et al evaluating valved holding chambers (VHCs) in children with acute wheezing provides important evidence addressing a common challenge in pediatric acute care, demonstrating that use of a VHC with higher in vitro drug-delivery efficiency was associated with clinically significant improvements in respiratory distress assessment instrument scores, hospitalization rates, and physiologic parameters. Given the limited coordination and variable inhalation patterns of infants and toddlers, optimizing bronchodilator delivery is clinically relevant. However, several issues warrant further consideration.

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