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For the second time in as many weeks, a leading California-based thoroughbred has been retired.

Nysos, who would have been favored in the $1-million Pacific Classic later this month at Del Mar and was a top early contender for the $5-million Breeders’ Cup Classic this fall, won’t race again, Coolmore America announced Monday.

The 5-year-old son of Nyquist is headed to stallion duty next year at Coolmore’s Ashford Stud in Versailles, Ky., the same farm where Journalism, another horse who was being pointed for those two races, was sent last month after his retirement because of injury.

In a statement, Coolmore said Nysos is sound and uninjured but “the decision was made following a routine diagnostic evaluation that revealed subtle imaging changes on a scan.” Trainer Bob Baffert and Nysos’ owners, Baoma Corp. and Coolmore, “unanimously agreed to take a strict precautionary approach, prioritizing the horse’s long-term health and safety above all else.”

Said Baffert: “Nysos is not hurt or injured, but taking a precautionary approach is strictly about doing what is right for the horse. With the minor changes shown on the evaluation, we simply don’t have the time needed to prepare him for the Breeders’ Cup the way we would want to. He has given us everything and retiring him completely sound and at the top of his game is the proper decision.”

Nysos retires after eight wins and two seconds in 10 lifetime races, with earnings of nearly $5.3 million. He was considered a top prospect for the 2024 Kentucky Derby but was injured that winter and didn’t race again for 15 months.

He returned in May 2025 and won four of five starts last year, including the Breeders’ Cup Dirt Mile at Del Mar. This year Nysos finished second to Forever Young in the Saudi Cup before defeating Journalism in the Met Mile in June at Saratoga, which turned out to be his last race.