Вход на сайт

Просмотр новости

Найдите то, что Вас интересует

STAT+: Sionna’s experimental cystic fibrosis pill falls flat in mid-stage trial

Дата публикации: 10-08-2026 12:03:17

A pill from Sionna Therapeutics provided no added benefit when combined with Vertex's cystic fibrosis blockbuster Trikafta, a blow to the biotech.

Основное содержимое страницы с новостью.

Experimental pill proved no better than Vertex’s blockbuster Trikafta alone
purple lungs ct Adobe

By Jason Mast

Aug. 10, 2026

General Assignment Reporter

Jason is a general assignment reporter, with particular focus on genetic medicine and rare disease. Confidential tips can be sent on Signal at JasonMast.77.

Sionna Therapeutics said Monday that its experimental pill for cystic fibrosis did not show any benefit when added onto Vertex Pharmaceuticals’ Trikafta in a Phase 2 trial. 

The company will no longer try to advance the drug, called SION-719, as an add-on therapy for CF patients. And it hinted at potential layoffs, saying it will “take actions to preserve capital while evaluating next steps.”

Sionna’s stock fell 90% in pre-market trading Monday morning. 

STAT+ Exclusive Story

Already have an account? Log in

STAT+

STAT+

This article is exclusive to STAT+ subscribers Unlock this article — plus daily coverage and analysis of the biotech sector — by subscribing to STAT+.

Already have an account? Log in

View All Plans

To read the rest of this story subscribe to STAT+.

Subscribe

  1. General Assignment Reporter

    Jason is a general assignment reporter, with particular focus on genetic medicine and rare disease. Confidential tips can be sent on Signal at JasonMast.77.

Схожие новости

#Наименование новостиТональностьИнформативностьДата публикации
1STAT+: Heart failure drug from Tenax Therapeutics fails in pivotal study05.3310-08-2026
2STAT+: Silence Therapeutics aims at Takeda with new data in rare blood cancer05.3310-08-2026
3STAT+: In surprise decision, FDA rejects radiopharma therapy expected to rival Novartis treatment07.7210-08-2026
4STAT+: Prime wins Beam arbitration, clearing path to clinic0709-07-2026
5STAT+: Pharmalittle: We’re reading about a Sanofi drug shortage, a Jazz Pharma deal, and more08.410-08-2026
6STAT+: Skylar Bio kicks off new gene therapy trial for deafness07.7211-08-2026
7STAT+: AstraZeneca, Ionis report major trial failure with heart disease drug-2709-07-2026
8STAT+: A shortage of two Sanofi medicines for Pompe disease rattles patients05.1809-08-2026
9Sionna Therapeutics (NASDAQ:SION) Given Hold Rating at Stifel Nicolaus010.3210-08-2026
10STAT+: FDA panel to weigh Grail’s Galleri test01010-08-2026

Классификация: Пресс-релизы. Схожих патентов: 0. Схожих новостей: 10. Тональность: 0. Информативность: 10.39. Источник: www.statnews.com.